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研究活動

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研究活動

生物化学分野の論文業績を紹介いたします。

2008年度論文発表

  1. Dohi, Y., Ikura, T., Hoshikawa, Y., Katoh, Y., Ota, K., Nakanome, A., Muto, A., Omura, S., Ohta, T., Ito, A., Yoshida, M., Noda, T., and Igarashi, K. Bach1 inhibits oxidative stress-induced cellular senescence by impeding p53 function on chromatin. Nature Struct. Mol. Biol. 15, 1246-1254 (2008).
  2. Ochiai, K., Muto, A., Tanaka, H., Takahashi, S. and Igarashi, K. Regulation of the plasma cell transcription factor Blimp-1 gene by Bach2 and Bcl6. Int. Immunol. 20, 453-460 (2008).
  3. Ito, N., Watanabe-Matsui, M., Igarashi, K., and Murayama, K. Crystal structure of the Bach1 BTB domain and its regulation of homodimerization. Genes Cells in press (2008).
  4. Kono, K., Harano, Y., Hoshino, H., Kobayashi, M., Bazett-Jones, D. P., Muto, A., Igarashi, K., and Tashiro, S. The mobility of Bach2 nuclear foci is regulated by SUMO-1 modification. Exp. Cell Res. 314, 903-913 (2008)
  5. Ochiai, S., Mizuno, T., Deie, M., Igarashi, K., Hamada, Y., and Ochi, M. Oxidative stress reaction in the meniscus of bach1 deficient mice: Potential prevention of meniscal degeneration. J. Orthop. Res. 26, 894-898 (2008).
  6. Sakoda, E., Igarashi, K., Sun, J., Kurisu, K., and Tashiro, S. Regulation of heme oxygenase-1 by transcription factor Bach1 in the mouse brain. Neuroscience Lett. 440, 160-165 (2008)
  7. Mito, S., Ozono, R., Oshima, T., Yano, Y., Watari, Y., Yamamoto, Y., Brydun, A., Igarashi, K. and Yoshizumi, M. Myocardial Protection Against Pressure Overload in Mice Lacking Bach1, a Transcriptional Repressor of Heme Oxygenase-1. Hypertension 51, 1570-1577 (2008).
  8. Watari, Y., Yamamoto, Y., Brydun, A., Ishida, T., Mito, S., Yoshizumi, M., Igarashi, K., Chayama, K., Ohshima, T., and Ozono, R. Ablation of the bach1 gene leads to the suppression of atherosclerosis in bach1 and apolipoprotein E double knockout mice. Hypertens. Res. 31, 783-792 (2008).
  9. Kassaovska-Bratinova, S., Yang, G., Igarashi, K. and Dennery, P.A. Bach1 modulates heme oxygenase-1 expression in the neonatal mouse lung. Pediatr. Res. in press (2008)
  10. Yamada, K., Tanaka, N., Nakanishi, K., Kamei, N., Ishikawa, M., Mizuno, T., Igarashi, K., and Ochi, M. Modulation of the secondary injury process after spinal cord injury in Bach1-deficient mice by heme oxygenase-1. J. Neurosurg. Spine. in press (2008)

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